The increased survival of patients with sickle cell disease (SCD) into adulthood leads an increased incidence of multiorgan dysfunction. The lung is one of the most common organs that may be involved in SCD. The pulmonary manifestations of SCD are the leading cause of morbidity and mortality in these patients. Although pulmonary manifestations of SCD are very common, they remain underdiagnosed by clinicians. The main pulmonary manifestations of SCD are acute chest syndrome, chronic dyspnea, asthma, sleep-disordered breathing, acute and chronic venous thromboembolic disease, pulmonary hypertension, and pulmonary fibrosis. Herein, the current knowledge of the pathophysiology, diagnosis, and treatment of pulmonary manifestations of SCD are reviewed.
Foreign body injuries are common injuries and foreign body penetrations may oc
cur in almost any part of the body. In the literature there are many reports includ
ing different kinds of piercing or penetrating injuries of the extremities. In this pa
per we report the case of a 19-year-old man who presented with a knife retained
in the forearm and our treatment strategy for removing the knife. We informed
our patient and took the consent form before the submission for publication.
Congenital diaphragmatic hernia is a progression into chest of abdominal organs depends on diaphragmatic defect during fetal development. Prevalence is 1 / 2500-3000 of live births. The most common seen hernia is Bochdalek (90%). In this presentation, late congenital diaphragmatic hernia is described in a patient treatment and follow-up process. Congenital diaphragmatic hernia is a congenital malformation manifested by diaphragmatic hernia, pulmonary hypoplasia and abdominal organ changes. The most common accepted theory of etiology is a problem in the closure of pleuroperitoneal canal. Left-sided hernias which are seen after puberty is rare. Our case is one of them. In conclusion, although the frequency of late congenital diaphragmatic hernia is 0.17–12 %, it is a clinical situation that may be encountered in intensive care practice. It must therefore be kept in mind.