Aim: Metabolic syndrome (MetS) is characterized by abdominal obesity, dyslipidemia, low-grade inflammation, insulin resistance, and hypertension that can lead to diabetes and cardiovascular disease. IL-22 is a member of the IL-10 cytokine family that has been shown to prevent or reverse obesity-induced glucose intolerance and insulin resistance; it also affects mucosal barrier maintenance and the prevention of endotoxemia and chronic…
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