Contribution of susceptibility weighted imaging sequence of MRI to diagnosis of parkinsons disease

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Aim: Parkinson disease is the second most common neurodegenerative dis-ease. In Parkinson disease, iron content in basal ganglia of the brain increas-es. In the present study the contribution of susceptibility weighted imaging (SWI) to the diagnosis of Parkinson disease was evaluated by investigating iron deposition in the basal ganglia of Parkinson disease patients. Material and Method: Thirty-five patients who had a clinical diagnosis of Parkinson disease and nineteen patients with a diagnosis of headache from the neurol-ogy clinic of our hospital from a similar age group were selected. Magnetic resonance images of the patients were compared retrospectively with the images obtained from the control group. Demographic data, disease dura-tion, age of first diagnosis and Parkinson clinical scores of the patients were recorded. Intensity measurements of the basal ganglia were obtained in SWI sequence. To make a quantitative analysis signal-noise ratio (SNR) was cal-culated from obtained measurements. Results: SNR results obtained from the basal ganglia with SWI sequence were significantly lower in the patient group compared with that from the control group (p<0.05). There was no correlation within the patient group between clinical score, disease dura-tion, patients’ age of first diagnosis and SNR results (p>0.05). Discussion: SWI sequence of magnetic resonance imaging may be used as supporting method for the diagnosis of Parkinson disease but it was not found very helpful in evaluating clinical severity, side of involvement and progression of the disease.

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  • Recieved: 27.02.2017
  • Accepted: 29.03.2017
  • Published Online: 29.03.2017
  • Printed: 01.05.2017
  • DOI: 10.4328/AEMED.108
  • Author: Derya Güclü, Ramazan Büyükkaya, Ömer Önbas, Fahri Halit Besir, Ayhan Öztürk, Mehmet Altan
  • Identifier: J Ann Eu Med 2017;5(2): 41-5
  • Index Page: 41-5
  • How to Cite: Derya Güclü, Ramazan Büyükkaya, Ömer Önbas, Fahri Halit Besir, Ayhan Öztürk, Mehmet Altan. Contribution of susceptibility weighted imaging sequence of MRI to diagnosis of parkinsons disease. J Ann Eu Med 2017;5(2): 41-5
  • Running Title: SWI sequence in parkinsons disease
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