An overview of pulmonary manifestations in sickle cell disease

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The increased survival of patients with sickle cell disease (SCD) into adulthood leads an increased incidence of multiorgan dysfunction. The lung is one of the most common organs that may be involved in SCD. The pulmonary manifestations of SCD are the leading cause of morbidity and mortality in these patients. Although pulmonary manifestations of SCD are very common, they remain underdiagnosed by clinicians. The main pulmonary manifestations of SCD are acute chest syndrome, chronic dyspnea, asthma, sleep-disordered breathing, acute and chronic venous thromboembolic disease, pulmonary hypertension, and pulmonary fibrosis. Herein, the current knowledge of the pathophysiology, diagnosis, and treatment of pulmonary manifestations of SCD are reviewed.

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  • Recieved: 23.03.2016
  • Accepted: 13.04.2016
  • Published Online: 13.04.2016
  • Printed: 01.05.2016
  • DOI: 10.4328/AEMED.84
  • Author: Ramazan Öcal
  • Identifier: J Ann Eu Med 2016;4(2): 53-6
  • Index Page: 53-6
  • How to Cite: Ramazan Öcal . An overview of pulmonary manifestations in sickle cell disease. J Ann Eu Med 2016;4(2): 53-6
  • Running Title: Lungs in Sickle Cell Disease
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